Sample Preparation in Bio Analytical Methods - a Review
نویسندگان
چکیده
This article reviews the recent developments in Bio-Analytical sample preparation techniques and gives an update on basic principles, Applications and comparative discussion on the advantages and limitations of each technique. Conventional Solid-Phase Extraction (SPE), Molecularly Imprinted Polymer SPE techniques are have been considered as methods of past. Developments in SPE techniques such as selective sorbents and in the overall approach to SPE, such as molecularly imprinted polymer SPE, have been addressed. Considerable literature has been published in the area of solid-phase micro-extraction and its different versions, e.g. stir bar sorptive extraction, and their application in the development of selective and sensitive bio analytical methods. MicroExtraction by Packed Sorbent, Stir-Bar Sorptive Extraction(SBSP), Pressurized liquid Extraction(PLE) are the advanced techniques in the extraction they are also covered in this review article.
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